Dr Husari's Medical and Basic Science Research

Dr Ahmad Husari  basic science research and interests include the parthenogenesis of lung injury and other organs injury secondary to the inhalation of harmful chemicals mainly hyperoxia and Tobacco smoke. Dr Husari has established a “state of the art” inhalational animal model that studied and documented the detrimental effects of combustible tobacco consumption and the use of electronic cigarette as well. 

Clinical Research

My clinical research is centered on identifying elements or interventions that may affect outcome or predict complications of patients undergoing medical or surgical procedures or intervention. 

· The six-minute walk test and sf-36 as a preoperative predictor of operative morbidity and mortality in patients undergoing high-risk surgery. 

The study concluded that the 6-minute walk test (6-MWT) and the Short Form-36 Health Survey (SF-36) are useful in predicting postoperative cardiopulmonary complications in patients undergoing high risk surgery. 

· The untold story of Dabigatran etexilate: alveolar hemorrhage in an elderly patient with interstitial pulmonary fibrosis. 

· Rivaroxaban for thromboprophylaxis in acutely ill medical patients

With the introduction of direct thrombin inhibitors and oral direct factor Xa inhibitors, we immediately reported our observations on potential complications. Our reports were published in New England Journal of Internal medicine and the Journal of thrombosis and thrombolysis.

Life Threatening Complications Post-Liposuction.

Ezzeddine H, Husari A, Nassar H, Kanso M, Nounou GE, Khalife M, Faraj W.

Aesthetic Plast Surg. 2018 Apr;42(2):384-387. doi: 10.1007/s00266-017-1058-x. Epub 2018 Jan 31.

PMID: 29387943

Pomegranate Juice Prevents the Formation of Lung Nodules Secondary to Chronic Cigarette Smoke Exposure in an Animal Model.

Husari A, Hashem Y, Zaatari G, El Sabban M.

Oxid Med Cell Longev. 2017;2017:6063201. doi: 10.1155/2017/6063201. Epub 2017 Nov 30

Acute Exposure to Cigarette Smoking Followed by Myocardial Infarction Aggravates Renal Damage in an In Vivo Mouse Model.

Kobeissy F, Shaito A, Kaplan A, Baki L, Hayek H, Dagher-Hamalian C, Nehme A, Ghali R, Abidi E, Husari A, Zeidan A, Zouein FA, Zibara K.

Oxid Med Cell Longev. 2017;2017:5135241. doi: 10.1155/2017/5135241. Epub 2017 Oct 22

Disruption of adherens junction and alterations in YAP-related proliferation behavior as part of the underlying cell transformation process of alcohol-induced oral carcinogenesis.

Husari A, Hülter-Hassler D, Steinberg T, Schulz SD, Tomakidi P.

Biochim Biophys Acta Mol Cell Res. 2018 Jan;1865(1):209-219. doi: 10.1016/j.bbamcr.2017.10.015. Epub 2017 Nov 2.

Electronic Cigarette Smoke Impairs Normal Mesenchymal Stem Cell Differentiation.

Shaito A, Saliba J, Husari A, El-Harakeh M, Chhouri H, Hashem Y, Shihadeh A, El-Sabban M.

Sci Rep. 2017 Oct 27;7(1):14281. doi: 10.1038/s41598-017-14634-z.

PMID: 29079789